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Does CIALIS Cause Vision Loss?

Conditions leading to a sudden decrease or loss of vision, including a condition called NAION, have been rarely reported in patients taking PDE5 inhibitors (oral ED [erectile dysfunction] medicines, including CIALIS). It is not possible to determine whether these cases are related directly to these medicines, to underlying conditions such as diabetes or high blood pressure, to a combination of these factors, or to other factors.

What is NAION?

NAION stands for nonarteritic anterior ischemic optic neuropathy. NAION is a condition in which the blood supply to the nerve that carries signals from the back of the eye to the brain is decreased. This is a rare but serious condition as it may lead to permanent loss of vision, including blindness.

What causes NAION?

The exact cause of NAION is unknown. NAION is more likely to occur in persons with the following conditions:
  • Previous history of NAION
  • Older age (greater than 50 years)
  • Diabetes mellitus
  • High blood pressure (hypertension)
  • High cholesterol
  • Cigarette smoking
  • A variation in the structure of the nerve that carries signals from the eye

There are other conditions that may be associated with NAION. Please talk to your health care professional.

How common is NAION?

NAION is a rare condition with 2-10 cases per 100,000 people over 50 years of age per year.

What are the symptoms of NAION?

Any sudden decrease or loss of vision may be a symptom of NAION. This may first be noticed after a person awakens from sleep. There is usually no pain associated with NAION.

What should I do if I have a sudden decrease or loss of vision?

If you experience a sudden decrease or loss of vision, stop taking any oral ED medication, including CIALIS, and call a doctor right away.

If I am being prescribed CIALIS for the first time, should I tell my doctor about any previous instance(s) of sudden decrease in vision?

As for any medicine, it is very important for you to tell your doctor about all your medical problems, including those in the past. Also, tell your doctor about all medications you're taking. If you have had NAION in one eye, you have a greater likelihood of getting it in the other eye. Only your doctor can determine if CIALIS is right for you.

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CIALIS is indicated for the treatment of erectile dysfunction.

Important Safety Information for CIALIS® (tadalafil)

Who Should Not Take CIALIS?
Do not take CIALIS if you:
  • take medicines called "nitrates" which are often prescribed for chest pain as the combination may cause an unsafe drop in blood pressure
  • use recreational drugs called "poppers" like amyl nitrite and butyl nitrite
  • are allergic to CIALIS or ADCIRCA ™ (tadalafil), or any of its ingredients
What Should I Tell My Healthcare Provider Before Taking CIALIS?
CIALIS is not right for everyone. Only your healthcare provider and you can decide if CIALIS is right for you.  Before taking CIALIS, tell your doctor about all your medical problems, particularly if you have or ever had:
  • an allergy to CIALIS or ADCIRCA or any of its ingredients
  • heart problems such as angina, heart failure, irregular heartbeats, or have had a heart attack
  • high or low blood pressure
  • stroke
  • liver or kidney problems
  • severe vision loss, including a condition called NAION
  • retinitis pigmentosa, a rare genetic (runs in families) eye disease
  • a deformed penis shape or Peyronie's disease
  • an erection that lasted more than 4 hours
  • blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia
Ask your healthcare provider if it is safe for you to have sexual activity. You should not take CIALIS if your healthcare provider has told you not to have sexual activity because of your health problems. Stop sexual activity and get medical help right away if you get symptoms such as chest pain, dizziness, or nausea during sex.

Can Other Medicines Affect CIALIS?

After taking a single tablet, some of the active ingredient of CIALIS remains in your body for more than 2 days. Tell your healthcare provider about all the medicines you take especially if you take:

  • medicines called “nitrates” which are often prescribed for chest pain
  • alpha blockers often prescribed for prostate problems
  • blood pressure medications
  • medicines for HIV or antifungal medications
  • erythromycin
  • other medicines or treatments for ED
  • CIALIS is also marketed as ADCIRCA for the treatment of pulmonary arterial hypertension. Do not take both CIALIS and ADCIRCA. Do not take sildenafil citrate (Revatio™) with CIALIS.
What Should I Avoid While Taking CIALIS?
  • Do not use other ED medicines or ED treatments while taking CIALIS.
  • Do not drink too much alcohol when taking CIALIS (for example, 5 glasses of wine or 5 shots of whiskey). Drinking too much alcohol can increase your chances of getting a headache or getting dizzy, increasing your heart rate, or lowering your blood pressure.
What Are The Possible Side Effects Of CIALIS?

The most common side effects with CIALIS are: headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose. These side effects usually go away after a few hours. Men who get back pain and muscle aches usually get it 12 to 24 hours after taking CIALIS. Back pain and muscle aches usually go away within 2 days. Call your healthcare provider if you get any side effect that bothers you or one that does not go away.

Uncommon side effects include:

An erection that won't go away: As with any ED tablet, in the rare event of an erection lasting more than 4 hours, seek immediate medical help to avoid long-term injury.

In rare instances, men taking prescription ED tablets (including CIALIS) reported a sudden decrease or loss of vision or hearing (sometimes with ringing in the ears and dizziness). It's not possible to determine if these events are related directly to the ED tablets or to other factors. If you have a sudden decrease or loss of vision or hearing, stop taking any ED tablet, including CIALIS and call your doctor right away.

CIALIS does not:
  • cure ED
  • increase a man's sexual desire
  • protect a man or his partner from sexually transmitted diseases, including HIV
  • serve as a male form of birth control

CIALIS is available by prescription only. For additional safety information, talk to your doctor about this medicine and see the full Patient Information.

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